association between t-786c polymorphism of endothelial nitric oxide synthase gene and level of the vessel dilation factor in patients with coronary artery disease

نویسندگان

fatemeh khaki-khatibi

ali reza yaghoubi

morteza ghojazadeh

mohammad rahbani-nobar

چکیده

various polymorphisms on endothelial nitric oxide synthase (enos) gene cause reduced production of no, the endothelial relaxing factor, and may accelerate the process of atherosclerosis. the study designed to investigate the frequency of t-786c polymorphism of the enos gene in patients suffering from coronary artery disease (cad) in north-west of iran. one hundred twenty subjects including 60 patients with angiographically diagnosed cad and 60 age and sex matched cad-free subjects as control were studied. the levels of nitric oxide in the samples were measured with the griess method. the genotype studies were carried using allele specific pcr. comparing with the control, reduced levels of no were noticed in the patient group (p

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Association between T-786C polymorphism of endothelial nitric oxide synthase gene and level of the vessel dilation factor in patients with coronary artery disease

Various polymorphisms on endothelial nitric oxide synthase (eNOs) gene cause reduced production of NO, the endothelial relaxing factor, and may accelerate the process of atherosclerosis. The study designed to investigate the frequency of T-786C polymorphism of the eNOs gene in patients suffering from coronary artery disease (CAD) in north-west of Iran. One hundred twenty subjects including 60 p...

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Association between T-786C polymorphism of endothelial nitric oxide synthase gene and level of the vessel dilation factor in patients with coronary artery disease

Various polymorphisms on endothelial nitric oxide synthase (eNOs) gene cause reduced production of NO, the endothelial relaxing factor, and may accelerate the process of atherosclerosis. The study designed to investigate the frequency of T-786C polymorphism of the eNOs gene in patients suffering from coronary artery disease (CAD) in north-west of Iran. One hundred twenty subjects including 60 p...

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عنوان ژورنال:
molecular biology research communications

ناشر: shiraz university press

ISSN 2322-181X

دوره 1

شماره 1 2012

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